Jacklin George Proteins that bind DNA are vital and crucial for living organisms. Our research is basically concerned with designing proteins which will be used to target specific DNA sequences to either repress or induce specific function. In terms of DNA-binding protein design, we are enriching our basic knowledge of the nature of the DNA […]
Ralston Smith About my research: I am designing a granzyme B binding peptide that will ultimately serve as a PET imaging agent for the determination of cancer immunotherapy efficacy. The work I am doing involves in silico and in vitro experimentation to characterize the granzyme B binding of a few peptide variants. The intention of his project […]
My research is doing protein engineering, specifically de novo protein design to make a ribose binding protein. By combing computational work and wet lab experiential I hope to understand the fundamental forces behind ribose binding to better understand ATP binding as a whole. Outside of the lab I enjoy reading, playing videogames, and dying my […]
Robert Spaine I am part of a group of students working towards the de novo design of an ATP binding protein. My contribution is the computationally-guided de novo design of proteins to bind adenine and triphosphate, respectively. The data gathered in this project will improve our understanding of the physical principles relevant to ATP binding. […]